114004-30-7Relevant academic research and scientific papers
Selective Monoesterification of Symmetrical Diols Using Resin-Bound Triphenylphosphine
Pathak, Gunindra,Rokhum, Lalthazuala
, p. 483 - 487 (2015)
Coupling reactions to make esters and amides are among the most widely used organic transformations. We report efficient procedures for amide bond formation and for the monoesterification of symmetrical diols in excellent yields without any requirement for high dilution or slow addition using resin-bound triarylphosphonium iodide. Easy purification, low moisture sensitivity, and good to excellent yields of the products are the major advantages of this protocol.
A microwave-assisted highly practical chemoselective esterification and amidation of carboxylic acids
Pathak, Gunindra,Das, Diparjun,Rokhum, Lalthazuala
, p. 93729 - 93740 (2016/10/21)
The ubiquitousness of esters and amide functionalities makes their coupling reaction one of the most sought-after organic transformations. Herein, we have described an efficient microwave-assisted synthesis of esters and amides. Soluble triphenylphosphine, in conjugation with molecular iodine, gave the desired products without the requirement for a base/catalyst. In addition, a solid-phase synthetic route is incorporated for the said conversion, which has added advantages over solution-phase pathways, such as low moisture sensitivity, easy handling, isolation of the product by simple filtration, and reusability. In short, our method is simple, mild, green, and highly chemoselective in nature.
Mesogens and methods for their synthesis and use
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Page/Page column 9; 27, (2008/06/13)
New, efficient methods for making novel platform molecules and polymerizable mesogens are provided, as well as the novel mesogens and methods of using same.
Pd-catalyzed silicon hydride reductions of aromatic and aliphatic nitro groups
Rahaim Jr., Ronald J.,Maleczka Jr., Robert E.
, p. 5087 - 5090 (2007/10/03)
(Chemical Equation Presented) Room-temperature reduction of aromatic nitro groups to amines can be accomplished in high yield, with wide functional group tolerance and short reaction times (30 min) using a combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS). Replacing PMHS/KF with triethylsilane allows aliphatic nitro groups to be reduced to their hydroxylamines.
Ytterbium triflate mediated selective deprotection of acetates
Sharma,Ilangovan
, p. 1963 - 1965 (2007/10/03)
Ytterbium triflate mediated selective deprotection of acetates in isopropyl alcohol at reflux temperature is reported. Unlike hafnium triflate, under the present reaction conditions aryl acetates also undergo deacetylation instead of Fries migration.
