114012-42-9

Basic information

• Product Name: 3-phenyloxetane-3-carboxylic acid
• Synonyms: 3-phenyloxetane-3-carboxylic acid;3-Phenyloxetane-3-carboxy...
• CAS NO: 114012-42-9
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.1846
• Mol File: 114012-42-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-phenyloxetane-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyloxetane-3-carboxylic acid(114012-42-9)
• EPA Substance Registry System: 3-phenyloxetane-3-carboxylic acid(114012-42-9)

Safety Data

• Hazardous Substances Data: 114012-42-9(Hazardous Substances Data)

Usage

General Description

3-phenyloxetane-3-carboxylic acid is a chemical compound with a molecular formula of C9H8O3. It is a oxetane derivative with a phenyl group attached to it, and a carboxylic acid group at the 3-position. It is a relatively rare compound and is not widely used or studied in comparison to other organic compounds. However, it may have potential applications in the field of medicinal chemistry or as a building block for the synthesis of more complex organic molecules. Its properties and potential uses have not been extensively researched, so further investigation may be needed to fully understand its potential applications.

Relevant articles and documents

Preparation method and application of 3-(substituted phenyl) oxetane-3-carboxylic acid and intermediate thereof

The preparation method comprises the following steps: taking 3-oxetanone (compound II) as an initial raw material, and carrying out Wittig reaction on the initial raw material and triethyl phosphonotriacetate under an alkaline condition to obtain a compound III; carrying out coupling reaction on the compound III and a boric acid compound IV to obtain a compound V; reducing the ester group of the compound V to generate a compound VI; carrying out nucleophilic substitution reaction on hydroxyl of the compound VI and sulfonyl chloride/sulfonic anhydride to generate a compound VII; reacting hydroxyl of the compound VI with a halogenating reagent to generate a compound VIII; carrying out elimination reaction on the compound VII or the compound VIII to generate a compound IX; and finally, oxidizing the double bonds of the compound IX to generate 3-(substituted phenyl) oxetane-3-carboxylic acid (compound I). The method is easy and convenient to operate and high in yield, the total yield can reach 35%, and large-scale production can be achieved.

Process for the preparation of 2,2-bis-chloro-methylalkanecarboxylic acid chlorides

A process for the preparation of a 2,2-bis-chloro-methyl-alkanecarboxylic acid of the formula STR1 in which R is hydrogen, alkyl, cycloalkyl or optionally substituted phenyl, which comprises reacting an oxetane-3-carboxylic acid of the formula STR2 or a salt thereof, with an inorganic acid chloride at a temperature between 20° C. and the boiling point of the reaction mixture. The products are known intermediates for fungicides and herbicides.