1140194-89-3Relevant academic research and scientific papers
Formation of α-hydroxyketones via irregular Wittig reaction
Okada, Hideki,Mori, Tomonori,Saikawa, Yoko,Nakata, Masaya
supporting information; experimental part, p. 1276 - 1278 (2009/09/05)
Αddition reactions of (1-methoxyalkyl)triphenylphosphonium ylides, derived from the corresponding Wittig salts and n-BuLi, to aldehydes were investigated. It was revealed that the betaine LiX complexes, the primary adducts, were converted to α-hydroxyketones, prior to the formation of oxaphosphetanes, by addition of aqueous NH4Cl at low temperature.
