114091-98-4

Upstream product

• 50622-60-1 3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 
• 155434-98-3 5-Acetoxymethyl-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid 2,2,2-tribromo-ethyl ester 
• 104705-80-8 5-[5-Iodo-4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-1H-pyrrol-2-ylmethyl]-3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 155434-80-3 dimethyl 1-benzyloxycarbonyl-9-carboxy-3,7-bis(methoxycarbonylmethyl)-5,10-dihydrodipyrrin-2,8-dipropionate 
• 207971-37-7 9-Benzyloxycarbonyl-4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-4,5-dihydodipyrrin-1(10H)-one 
• 207974-92-3 1-Benzyloxycarbonyl-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)dipyrromethane 
• 51912-05-1 5-acetoxymethyl-4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 
• 1026177-13-8 C₅₁H₅₆ClN₃O₁₆ 

Downstream Products

• 114125-37-0 dibenzyl 2,8,13-tris(2-methoxycarbonylethyl)-3,7,12-tris(methoxycarbonylmethyl)-5,10,15,17-tetrahydrotripyrrin-1,14-dicarboxylate 

Relevant academic research and scientific papers

Biosynthesis of porphyrins and related macrocycles. Part 48. The rearrangement of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis

It is proposed that the biosynthesis of uroporphyrinogen III 3, the parent precursor of the natural porphyrins, chlorins and corrins, involves a 2H-pyrrole (pyrrolenine) 2 as a key intermediate. Model pyrrolenines have now been used to show that (a) pyrro

Selectivity in the Rearrangement of a Di(pyrrolylmethyl)-2H-pyrrole

A di(pyrrolylmethyl)-2H-pyrrole has been synthesised and its ready acid-catalysed rearrangement shows that one of the two possible modes of cleavage is preferred; this mode corresponds to that required for the formation of uroporphyrinogen-III from the putative spiro intermediate.