114092-40-9Relevant academic research and scientific papers
Highly selective Diels-Alder reactions of directly connected enyne dienophiles
Dai, Mingji,Sarlah, David,Yu, Maolin,Danishefsky, Samuel J.,Jones, Gavin O.,Houk
, p. 645 - 657 (2007)
The paper describes the course of cycloadditions of Diels-Alder dienophiles containing linked enyne sites, each substituted with activating groups. Consistently, it was found that in the enyne cases the Diels-Alder reaction occurred specifically at the ac
A Directed Aldol Approach to (+)-Milbemycin β3
Kocienski, Philip J.,Street, Stephen D. A.,Yeates, Clive,Campbell, Simon F.
, p. 2171 - 2182 (2007/10/02)
Key steps in a total synthesis of (+)-milbemycin β3 are the construction of the 1,7-dioxaspiroundecane (10) by a Lewis acid-catalysed intramolecular directed aldol reaction and the use of sulphone-based olefination reactions for the constr
