1140948-78-2Relevant articles and documents
Indolylarylsulfones bearing natural and unnatural amino acids. discovery of potent inhibitors of hiv-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie b4 virus
Piscitelli, Francesco,Coluccia, Antonio,Brancale, Andrea,La Regina, Giuseppe,Sansone, Anna,Giordano, Cesare,Balzarini, Jan,Maga, Giovanni,Zanoli, Samantha,Samuele, Alberta,Cirilli, Roberto,La Torre, Francesco,Lavecchia, Antonio,Novellino, Ettore,Silvestri, Romano
experimental part, p. 1922 - 1934 (2009/12/31)
New potent indolylarylsulfone (IAS) HIV-1 NNRTIs were obtained by coupling natural and unnatural amino acids to the 2-carboxamide and introducing different electron-withdrawing substituents at position 4 and 5 of the indole nucleus. The new IASs inhibited
