114113-85-8Relevant academic research and scientific papers
Synthesis of a Naturally Occurring Dihydrohomopteridine Insect Metabolite, 6-Acetyl-2-amino-7,8-dihydro-9H-pyrimidodiazepin-4(3H)-one
Boyle, Peter H.,Hughes, Enid M.,Khattab, Hassan A.,Lockhart, Ronan J.
, p. 2071 - 2077 (2007/10/02)
The naturally occurring dihydrohomopterin derivative 6-acetyl-2-amino-7,8-dihydro-9H-pyrimidodiazepin-4(3H)-one (1) has been synthesised from 1-amino-4,4-diethoxypentan-3-ol (10) and 2-amino-6-chloro-5-nitropyrimidin-4(3H)-one (3).A novel tricyclic intermediate, 2,2a-dihydroxy-2-methyl-6-nitro-1,2,2a,3,4,5-hexahydro-1,5,8,8b-tetra-aza-acenaphthylen-7-one was isolated.
