114119-89-0Relevant articles and documents
Peptide Synthesis. Part 12. 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Esters of Fluorenylmethoxycarbonyl Amino Acids as Self-indicating Reagents for Solid Phase Peptide Synthesis
Atherton, Eric,Holder, Jill L.,Meldal, Morten,Sheppard, Robert C.,Valerio, Robert M.
, p. 2887 - 2894 (2007/10/02)
The preparation and characterisation of 3,4-dihydro-4-oxo-1,2,3-benzotriazinyl esters (1) of Fmocamino acids and their use in solid phase peptide synthesis is described.Ionisation of the liberated hydroxy component (2) by the starting resin-bound amine pr