114127-76-3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 15176-29-1 edoxudine 

Downstream Products

• 115179-60-7 5'-(4-chlorobenzylamino)-2',5'-dideoxy-5-ethyluridine 
• 115179-63-0 2',5'-dideoxy-5-ethyl-5'-(N-methyl-N-benzylamino)uridine 
• 115179-61-8 2',5'-dideoxy-5-ethyl-5'-[1(R)-phenylethylamino]uridine 
• 115179-62-9 2',5'-dideoxy-5-ethyl-5'-[1(S)-phenylethylamino]uridine 
• 116316-47-3 5'-benzylthio-2',5'-dideoxy-5-ethyluridine 
• 115179-57-2 5'-(2-bromobenzylamino)-2',5'-dideoxy-5-ethyluridine 
• 115179-67-4 5'-[1(S)-benzylethylamino]-2',5'-dideoxy-5-ethyluridine 
• 115179-54-9 5'-[2-(2,6-dichlorophenyl)ethylamino]-2',5'-dideoxy-5-ethyluridine 
• 115179-55-0 5'-(2,3-dichlorobenzylamino)-2',5'-dideoxy-5-ethyluridine 
• 115179-58-3 5'-[2-(2-bromophenyl)ethylamino]-2',5'-dideoxy-5-ethyluridine 
• 115179-66-3 2',5'-dideoxy-5-ethyl-5'-(N-methylphenylethylamino)uridine 
• 116316-50-8 5'-(2,6-dichlorobenzylthio)-2',5'-dideoxy-5-ethyluridine 
• 115179-53-8 5'-(2,6-dichlorobenzylamino)-2',5'-dideoxy-5-ethyluridine 
• 116316-48-4 5'-(2-chlorobenzylthio)-2',5'-dideoxy-5-ethyluridine 

Relevant academic research and scientific papers

Pyrimidine derivatives, pharmaceutical compositions and method of using same

Compounds of the formula STR1 wherein A is C1-8 -alkylene, R1 is halogen, C1-4 -alkyl or halo-(C1-4 -alkyl), R2 is hydrogen, hydroxy or acyloxy, R3 is hydrogen or C1-4 -alkyl, R4 is aryl or aryloxy and X is O or NH, and tautomers thereof are described. The compounds of formula I and their tautomers possess antiviral activity and can be used in the form of medicaments for the control and prevention of viral infections.

2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents

A compound which exhibits antiviral activity towards HTLV-III/LAV, having the formula: STR1 wherein R4 is O or NH; R5 is a C2-4 alkyl group or a C3-4 cycloalkyl group, wherein said alkyl group or cycloalkyl grou