114143-70-3

Upstream product

• 114143-69-0 2,3-bis<(3,4-dimethoxybenzyl)amino>-1-<(2-tetrahydropyranyl)oxy>propane 
• 21709-18-2 N-(2,6-dichlorophenyl)-1,1-dichloromethanimine 
• 101857-33-4 2,3-diamino-1-<(2-tetrahydropyranyl)oxy>propane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 114143-68-9 2,3-bis<(3,4-dimethoxybenzylidene)amino>-1-<(2-tetrahydropyranyl)oxy>propane 

Downstream Products

• 114143-71-4 2-<(2,6-dichlorophenyl)imino>-1,3-bis(3,4-dimethoxybenzyl)-4-(hydroxymethyl)imidazolidine 
• 114143-73-6 2-<(2,6-dichlorophenyl)imino>-4-<<<3-(tert-butylamino)-2-hydroxypropyl>oxy>methyl>imidazolidine 
• 114143-72-5 2-<(2,6-dichlorophenyl)imino>-1,3-bis(3,4-dimethoxybenzyl)-4-<<<3-(tert-butylamino)-2-hydroxypropyl>oxy>methyl>imidazolidine 

Relevant academic research and scientific papers

Synthesis and ocular antihypertensive activity of new imidazolidine derivatives containing a β-blocking side chain

The syntheses of new phenylimidazolidine derivatives (3-6)1 containing a propanolamine oxime or an oxypropanolamine moiety attached either to the aromatic or to the imidazolidine ring are described. These compounds were evaluated for potential

IMINOIMIDAZOLIDINES USEFUL IN LOWERING INTRAOCULAR PRESSURE

Antiglaucoma compounds having beta adrenoreceptor antagonist properties and alpha adrenoreceptor antagonist properties are described. The compounds comprise a beta blocker-derived moiety designed to provide beta antagonist properties and an imidazolidine moiety designed to provide alpha-antagonist properties. Methods of synthesizing the compounds are also described. The compounds are useful in the treatment of glaucoma due to their ability to lower elevated intraocular pressure.

THE 3,4-DIMETHOXYBENZYL GROUP: A PROTECTIVE GROUP FOR NEW 2-IMINO-IMIDAZOLIDINE DERIVATIVES

The 3,4-dimethoxybenzyl group has been used to protect 2-imino-imidazolidine derivatives, so we could realize selective O-alkylation, to obtain new clonidine derivatives.