1141497-21-3

Basic information

• Product Name: C₂₇H₄₃N₃O₃
• CAS NO: 1141497-21-3
• Molecular Weight: 457.657
• Mol File: 1141497-21-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₄₃N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₄₃N₃O₃(1141497-21-3)
• EPA Substance Registry System: C₂₇H₄₃N₃O₃(1141497-21-3)

Safety Data

• Hazardous Substances Data: 1141497-21-3(Hazardous Substances Data)

Upstream product

• 917807-05-7 N-[(1S)-3-oxo-1-phenylbutyl]cyclobutanecarboxamide 
• 313977-45-6 tert-butyl N-ethyl-N-(4-piperidyl)carbamate 

Relevant articles and documents

1-Amido-1-phenyl-3-piperidinylbutanes - CCR5 antagonists for the treatment of HIV. Part 1

The development of a new class of CCR5 antagonist replacing the tropane core of maraviroc by piperidine with a branched N-substituent is described. Compound 15h shows good whole cell antiviral activity together with microsomal stability and only weak activity at the hERG ion channel.