1141508-44-2Relevant academic research and scientific papers
Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride
Kielland, Nicola,Vendrell, Marc,Lavilla, Rodolfo,Chang, Young-Tae
supporting information; scheme or table, p. 7401 - 7403 (2012/10/08)
Histamine is a biogenic amine with fundamental roles in circulatory and immune systems. We report a fluorescent small molecule (Histamine Blue) for imaging intracellular histamine in live basophils and macrophages. Histamine Blue is a fluorescent mesoionic acid fluoride that turns on upon reaction with histamine. The selective response of Histamine Blue enabled the visualization of intracellular histamine under different physiological conditions.
Multicomponent access to functionalized mesoionic structures based on TFAA activation of isocyanides: Novel domino reactions
Arevalo, Maria Jose,Kielland, Nicola,Masdeu, Carme,Miguel, Miriam,Isambert, Nicolas,Lavilla, Rodolfo
experimental part, p. 617 - 625 (2009/07/17)
The reactions of azines (isoquinolines, pyridine) with TFAA and isocyanides in a new domino process yield mesoionic acid fluorides with an imidazo[1,2-α]azine core. This multi-component reaction has a general character, tolerating a wide range of substitu
