1141510-03-3

Basic information

• Product Name: (6R)-3-[(1R)-1-[13C₆]-(3-aminophenyl)-1-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one
• Synonyms: (6R)-3-[(1R)-1-[13C₆]-(3-aminophenyl)-1-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one
• CAS NO: 1141510-03-3
• Molecular Weight: 399.46
• Mol File: 1141510-03-3.mol

Chemical Properties

• CAS DataBase Reference: (6R)-3-[(1R)-1-[13C₆]-(3-aminophenyl)-1-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-3-[(1R)-1-[13C₆]-(3-aminophenyl)-1-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one(1141510-03-3)
• EPA Substance Registry System: (6R)-3-[(1R)-1-[13C₆]-(3-aminophenyl)-1-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one(1141510-03-3)

Safety Data

• Hazardous Substances Data: 1141510-03-3(Hazardous Substances Data)

Upstream product

• 1141510-02-2 (6R)-4-hydroxy-3-[1-[13C₆]-(3-nitrophenyl)-1-propyl]-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one 

Downstream Products

• 1141510-04-4 N-[3-{(1R)-(5,6-dihydro-4-hydroxy-2-oxo-6(R)-phenethyl-6-propyl-2H-pyran-3-yl)-[1-14C]propyl}phenyl]-5-trifluoromethylpyridine-2-sulfonamide 

Relevant articles and documents

Synthesis of [14C] - and [13C6]-labeled tipranavir and its potential hydroxyl metabolite and the glucuronide conjugate

Tipranavir or Aptivus is a non-peptidic protease inhibitor approved for the combination treatment with ritonavir of HIV infection. Tipranavir labeled with radioactive and stable isotopes of carbon was required for drug metabolism (excretion, distribution,