1141510-06-6

Basic information

• Product Name: N-Hydroxy Tipranavir
• Synonyms: N-Hydroxy Tipranavir;N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-N-hydroxy-5-(trifluoroMethyl)-2-pyridinesulfonaMide;N-hydroxy-N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide
• CAS NO: 1141510-06-6
• Molecular Formula: C₃₁H₃₃F₃N₂O₆S
• Molecular Weight: 618.6637296
• Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1141510-06-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Hydroxy Tipranavir(CAS DataBase Reference)
• NIST Chemistry Reference: N-Hydroxy Tipranavir(1141510-06-6)
• EPA Substance Registry System: N-Hydroxy Tipranavir(1141510-06-6)

Safety Data

• Hazardous Substances Data: 1141510-06-6(Hazardous Substances Data)

Usage

Uses

A potential metabolite of Tipranavir.

Upstream product

• 1141510-05-5 (6R)-4-hydroxy-3-[(R)-1-(3-hydroxyaminophenyl)-1-propyl]-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one 
• 174485-72-4 5-trifluoromethyl-pyridin-2-ylsulfonylchloride 

Relevant articles and documents

Synthesis of [14C] - and [13C6]-labeled tipranavir and its potential hydroxyl metabolite and the glucuronide conjugate

Tipranavir or Aptivus is a non-peptidic protease inhibitor approved for the combination treatment with ritonavir of HIV infection. Tipranavir labeled with radioactive and stable isotopes of carbon was required for drug metabolism (excretion, distribution,