1141669-61-5 Usage
Description
4-Boc-2-homomorpholinecarboxylic Acid, also known as 4-(tert-butoxycarbonyl)-2-homomorpholinecarboxylic acid, is a chemical compound with the molecular formula C12H21NO5. It is a derivative of morpholine, featuring a tert-butoxycarbonyl (Boc) protecting group attached to the carboxylic acid functional group. 4-Boc-2-homomorpholinecarboxylic Acid is notable for its potential applications in organic synthesis and pharmaceutical research, where it serves as a versatile building block for the synthesis of various compounds. Its unique structure and reactivity contribute to its value in the development of new drugs and materials. However, it is crucial to handle this compound with care due to potential risks to human health and the environment if mismanaged.
Uses
Used in Organic Synthesis:
4-Boc-2-homomorpholinecarboxylic Acid is used as a building block for the synthesis of various organic compounds. Its Boc-protected carboxylic acid group allows for selective reactions, making it a valuable intermediate in the preparation of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-Boc-2-homomorpholinecarboxylic Acid is used as a key intermediate in the development of new drugs. Its unique reactivity and structure enable the creation of novel drug candidates with potential therapeutic applications.
Used in Material Science:
4-Boc-2-homomorpholinecarboxylic Acid is also utilized in material science for the development of new materials. Its chemical properties can be harnessed to create innovative materials with specific properties for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1141669-61-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,1,6,6 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1141669-61:
(9*1)+(8*1)+(7*4)+(6*1)+(5*6)+(4*6)+(3*9)+(2*6)+(1*1)=145
145 % 10 = 5
So 1141669-61-5 is a valid CAS Registry Number.
1141669-61-5Relevant articles and documents
Lipase Catalyzed Regioselective Lactamization as a Key Step in the Synthesis of N-Boc (2R)-1,4-Oxazepane-2-Carboxylic Acid
Aurell, Carl-Johan,Karlsson, Staffan,Pontén, Fritiof,Andersen, S?ren M.
, p. 1116 - 1119 (2014)
A synthesis of N-Boc (2R)-1,4-oxazepane-2-carboxylic acid 1 has been developed in 39% yield over seven steps starting from methyl (2R)-glycidate 2. The key step was a lipase-catalyzed regioselective lactamization of amino diester 5 into seven-membered lactam 6. The transformation was performed using SpinChem rotating flow cell technology which simplified the work up and the recycling of the enzyme. Subsequent N-Boc protection followed by chemoselective borane reduction of the lactam moiety afforded 4-tert-butyl 2-methyl (2R)-1,4-oxazepane-2,4-dicarboxylate 8. Finally, hydrolysis mediated by LiBr/Et3N in wet acetonitrile yielded the title compound (2R)-4-(tert-butoxycarbonyl)-1,4-oxazepane-2-carboxylic acid 1.
CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS
-
, (2015/08/04)
The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.
