1141669-69-3

Basic information

• Product Name: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine
• Synonyms: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine;2-AMino-5-Cbz-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine;2-AMino-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester
• CAS NO: 1141669-69-3
• Molecular Formula: C14H15N3O2S
• Molecular Weight: 289
• Mol File: 1141669-69-3.mol

Chemical Properties

• Boiling Point: 503.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.373±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.21±0.20(Predicted)
• CAS DataBase Reference: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(1141669-69-3)
• EPA Substance Registry System: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(1141669-69-3)

Safety Data

• Hazardous Substances Data: 1141669-69-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine is utilized as a building block for the synthesis of novel biologically active molecules due to its distinctive structural features. Its potential to form various chemical entities makes it valuable in the design and development of new pharmaceutical agents.
Used in Drug Development:
In the pharmaceutical industry, 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine serves as a key intermediate in the creation of innovative drug candidates. Its unique structure allows for the exploration of new therapeutic avenues, particularly for conditions that require targeted and specific molecular interactions.
Used in Organic Synthesis:
2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine is employed as a versatile synthetic intermediate in organic synthesis. Its ability to participate in various chemical reactions facilitates the production of a wide range of organic compounds, contributing to the advancement of chemical research and the discovery of new materials and substances.

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Relevant articles and documents

Preparation 2 - amino - 5 - CBZ - 4, 5, 6, 7 - tetrahydro-thiazolo [5, 4 - C] pyridine of the new method (by machine translation)

The invention discloses a process for preparing 2 - amino - 5 - CBZ - 4, 5, 6, 7 - tetrahydro-thiazolo [5, 4 - C] pyridine of the new method, comprises the following steps: N - tert-butoxycarbonyl - 4 - piperidone in pyridine with sulfur and single cyanamide mixed heating reaction→cooling→filtering→washed with an organic solvent, and dried to obtain a pale yellow solid product→in dichloromethane in trifluoroacetic acid is mixed with low-temperature reaction, concentrated→with triethylamine in dichloromethane in the mixed low-temperature drop chlorination benzyl formate, stirring reaction→[...]→dichloromethane extraction, the organic phase water, salt water washing, drying, filtering and concentrated to obtain crude product→ethyl acetate beating, the final product is obtained yellow solid. The invention of cheap price for raw materials to replace the original high price of the raw material for preparing the final product, to avoid the original ring-brominated by-product when many routes, not only the operation is simple, convenient purification, the cost is reduced, high yield, favorable to the industrialized production and cost control. (by machine translation)