1141669-69-3

Basic information

• Product Name: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine
• Synonyms: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine;2-AMino-5-Cbz-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine;2-AMino-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester
• CAS NO: 1141669-69-3
• Molecular Formula: C14H15N3O2S
• Molecular Weight: 289
• Mol File: 1141669-69-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 503.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.373±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.21±0.20(Predicted)
• CAS DataBase Reference: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(1141669-69-3)
• EPA Substance Registry System: 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine(1141669-69-3)

Safety Data

• Hazardous Substances Data: 1141669-69-3(Hazardous Substances Data)

Usage

General Description

2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine is a complex chemical compound that consists of a thiazole ring fused with a pyridine ring. It contains an amino group and a carboxybenzyl (Cbz) group attached to the nitrogen atom in the thiazole ring. 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine has potential applications in medicinal chemistry and drug development due to its structural features, which make it a candidate for the development of biologically active molecules. The unique structure of 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo[5,4-c]pyridine makes it a promising candidate for further research and development in the field of pharmaceuticals and organic synthesis.

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Relevant articles and documents

Preparation 2 - amino - 5 - CBZ - 4, 5, 6, 7 - tetrahydro-thiazolo [5, 4 - C] pyridine of the new method (by machine translation)

The invention discloses a process for preparing 2 - amino - 5 - CBZ - 4, 5, 6, 7 - tetrahydro-thiazolo [5, 4 - C] pyridine of the new method, comprises the following steps: N - tert-butoxycarbonyl - 4 - piperidone in pyridine with sulfur and single cyanamide mixed heating reaction→cooling→filtering→washed with an organic solvent, and dried to obtain a pale yellow solid product→in dichloromethane in trifluoroacetic acid is mixed with low-temperature reaction, concentrated→with triethylamine in dichloromethane in the mixed low-temperature drop chlorination benzyl formate, stirring reaction→[...]→dichloromethane extraction, the organic phase water, salt water washing, drying, filtering and concentrated to obtain crude product→ethyl acetate beating, the final product is obtained yellow solid. The invention of cheap price for raw materials to replace the original high price of the raw material for preparing the final product, to avoid the original ring-brominated by-product when many routes, not only the operation is simple, convenient purification, the cost is reduced, high yield, favorable to the industrialized production and cost control. (by machine translation)