114171-31-2Relevant academic research and scientific papers
The Mechanism of Two Reactions leading to Isomeric 2-(N,N-Disubstituted Amino)thiazol-5-yl Ketones
Challacombe, Katherine,Leach, Susan E.,Plackett, Simon J.,Meakins, G. Denis
, p. 2213 - 2218 (2007/10/02)
A study has been made of the condensations between N-acyl-N',N'-disubstituted thioureas and α-halogeno ketones , and between N,N-disubstituted thioureas and 2-bromo-1,3-diketones .The mechanistic details were elucidated by usi
A Study of Three Reactions leading to Isomeric 2-(N,N-Disubstituted Amino)thiazol-5-yl Ketones
Funnell, Richard A.,Meakins, G. Denis,Peach, Josephine M.,Price, Susan J.
, p. 2311 - 2316 (2007/10/02)
N-Imidoyl-N,N-disubstituted thioureas react with α-halogeno ketones in the presence of triethylamine to give the expected 2-(N,N-disubstituted amino)thiazol-5-yl ketones in high yield.The corresponding reactions of N-acyl-N,N-disubstituted thioureas lead
THE USE OF PROTIUM AND DEUTERIUM ANALOGUES IN MECHANISTIC STUDIES OF THIAZOLE SYNTHESES
Challacombe, Katherine,Plackett, Simon J.,Meakins, G. Denis
, p. 5767 - 5768 (2007/10/02)
The mechanism of two reactions which give isomeric thiazol-5-yl ketones have been elucidated by work with substrates containing pairs of acyl groups and their deuterium-substituted analogues.
