1141777-14-1 Usage
General Description
"(R)-3-amino-1-(3-(cyclohexylmethoxy)phenyl)propan-1-ol" is a chemical compound that belongs to the class of amines and alcohols. The compound consists of a cyclohexylmethoxyphenyl group attached to a three-carbon chain, which terminates in an amino and hydroxyl group. (R)-3-amino-1-(3-(cyclohexylmethoxy)phenyl)propan-1-ol has potential applications in the pharmaceutical industry as it contains an amine and an alcohol functional group, making it suitable for use as an intermediate in the synthesis of various drugs. It also has the potential to be used in the development of new therapeutic agents for the treatment of various medical conditions. (R)-3-amino-1-(3-(cyclohexylmethoxy)phenyl)propan-1-ol's stereochemistry is indicated by the "(R)" prefix, indicating that it is the enantiomer with the highest priority group on the third carbon pointing to the right.
Check Digit Verification of cas no
The CAS Registry Mumber 1141777-14-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,1,7,7 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1141777-14:
(9*1)+(8*1)+(7*4)+(6*1)+(5*7)+(4*7)+(3*7)+(2*1)+(1*4)=141
141 % 10 = 1
So 1141777-14-1 is a valid CAS Registry Number.
1141777-14-1Relevant articles and documents
Rapid Access to γ-Amino-α-aryl Alcohol Scaffolds via an Enamine-Based Heck Coupling
Li, Bowen,Tochtrop, Gregory P.
, p. 3851 - 3855 (2022/03/02)
The γ-amino-α-aryl alcohol is a key functional group for the design of inhibitors directed toward a critical family of metabolic enzymes. Here we report the transformation of simple aryl halides to a highly functionalized benzyl (3-oxo-3-arylpropyl)carbamate intermediate that can rapidly be converted to a high value γ-amino-α-aryl alcohol. This chemistry is realized through a two-step process involving an enamine-based Heck coupling (EBHC) followed by a one-pot catalytic Cbz-deprotection and ketone reduction of EBHC products.
COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
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Page/Page column 235; 236, (2010/05/13)
Provided are compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
