1141874-52-3

Basic information

• Product Name: methyl 2-methylene-3-phenyl-4-(pyridin-2-yl)butanoate
• Synonyms: methyl 2-methylene-3-phenyl-4-(pyridin-2-yl)butanoate
• CAS NO: 1141874-52-3
• Molecular Weight: 267.327
• Mol File: 1141874-52-3.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-methylene-3-phenyl-4-(pyridin-2-yl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-methylene-3-phenyl-4-(pyridin-2-yl)butanoate(1141874-52-3)
• EPA Substance Registry System: methyl 2-methylene-3-phenyl-4-(pyridin-2-yl)butanoate(1141874-52-3)

Safety Data

• Hazardous Substances Data: 1141874-52-3(Hazardous Substances Data)

Upstream product

• 103547-97-3 methyl 2-(bromomethyl)-3-phenylacrylate 
• 118183-76-9 allyl 2-pyridylacetate 
• 109-06-8 α-picoline 
• 1352054-21-7 Br^(1-)*C₁₇H₁₈NO₂⁽¹⁺⁾ 
• 956833-12-8 methyl 2-{[(tert-butoxycarbonyl)oxy](phenyl)methyl}acrylate 

Relevant articles and documents

Direct C(sp3)–H allylation of 2-alkylpyridines with Morita–Baylis–Hillman carbonates via a tandem nucleophilic substitution/aza-Cope rearrangement

A base- and catalyst-free C(sp3)–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem SN2’ type nucleophilic substitution followed by an aza-Cope rearrangement. Various alkyl substituents on 2-alkylpyridines were tolerated in the reaction to give the allylation products in 26–91% yields. The developed method provides a straightforward and operational simple strategy for the allylic functionalization of 2-alkypyridine derivatives.

Direct one-pot introduction of 2-methylpyridines to Baylis-Hillman adducts via base-mediated 3-aza-Cope rearrangement

An efficient and regioselective introduction method of 2-methylpyridines to the secondary position of Baylis-Hillman adducts has been developed. A base treatment of 2-methylpyridinium salt of Baylis-Hillman bromide generated N-allylenamine intermediate wh

An expedient aralkylation of Baylis-Hillman adduct via the Pd-catalyzed decarboxylative protonation strategy

An expedient protocol of aralkylation of Baylis-Hillman adducts has been developed. This method used Pd-catalyzed decarboxylative protonation strategy to the allyl ester precursor that was made from the Baylis-Hillman adduct and allyl phenylacetate.