1141925-05-4

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl (2-hydroxy-5-nitrophenyl)carbamate is used as a reagent or intermediate for the synthesis of various drugs and organic compounds. Its high stability and low reactivity make it a reliable component in the development of pharmaceuticals.
Used in Medicinal Chemistry Research:
BHNC is utilized as an important building block due to its unique structure that allows for selective modification of functional groups, facilitating the creation of new and innovative pharmaceutical compounds.
Used in Organic Chemistry:
In the field of organic chemistry, tert-butyl (2-hydroxy-5-nitrophenyl)carbamate is used for its versatile and valuable properties in chemical synthesis, contributing to the advancement of organic compounds and reactions.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 99-57-0 2-hydroxy-5-nitroaniline 

Downstream Products

• 1415231-31-0 (E)-N-(3-amino-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide 
• 1415231-33-2 (S,E)-2-amino-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)-5-(3-nitroguanidino)pentanamide hydrochloride 
• 1415231-34-3 (E)-4-amino-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)butanamide hydrochloride 
• 1415231-36-5 (S,E)-N-(3-(2-amino-3-(1H-indol-3-yl)propanamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-37-6 (S,E)-N-(3-(2-amino-3-phenylpropanamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-38-7 (S,E)-2-amino-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)-3-methylbutanamide hydrochloride 
• 1415231-39-8 (S,E)-2-amino-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)-4-(methylthio)butanamide hydrochloride 
• 1415231-41-2 (S,E)-N-(3-(2-amino-3-hydroxypropanamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-42-3 (S,E)-N-(3-(2-aminopropanamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-43-4 (E)-N-(3-(2-aminoacetamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-45-6 (S,E)-2-amino-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)-4-methylpentanamide hydrochloride 
• 1415231-46-7 (E)-N-(3-(3-aminopropanamido)-4-hydroxyphenyl)-3-(furan-2-yl)acrylamide hydrochloride 
• 1415231-47-8 (2S,4R)-N-(5-((E)-3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)-4-hydroxypyrrolidine-2-carboxamide hydrochloride 
• 1415231-48-9 (S,E)-N-(5-(3-(furan-2-yl)acrylamido)-2-hydroxyphenyl)pyrrolidine-2-carboxamide hydrochloride 

Relevant academic research and scientific papers

Syntheses and kinetic studies of cyclisation-based self-immolative spacers

Kinetic analysis of the disassembly of self-immolative spacers based on cyclisation processes was performed. Five compounds were synthesized belonging to two different series, and their kinetic constants were determined. Electron-donating substituents gav

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The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

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The present invention provides compounds, compositions thereof, and methods of using the same.

HETEROARYL COMPOUNDS AND USES THEREOF

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Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo

Enlightened by some flavonoid compounds, which had been found as influenza neuraminidase inhibitors, we designed and synthesized a series of novel compounds containing different amino acid fragments. We also reported a simple synthetic route from oseltamivir to prepare its active form which was used as the positive control. The result of enzyme inhibition assay indicated that all the designed compounds displayed weak inhibitory activity against neuraminidase. However, they showed moderate anti-avian H5N1 influenza virus activity in chick embryo. Besides interfering with the function of neuraminidase, these compounds seemed to inhibit the replication of influenza virus by some other mechanism which deserved deep study.