1142173-29-2Relevant academic research and scientific papers
Platinum-catalyzed consecutive C-N bond formation-[1,3] shift of carbamoyl and ester groups
Nakamura, Itaru,Sato, Yusuke,Konta, Sayaka,Terada, Masahiro
supporting information; experimental part, p. 2075 - 2077 (2009/09/05)
The reaction of ortho-alkynylphenylureas 1 having a carbamoyl group attached to the nitrogen atom proceeded in the presence of catalytic amounts of PtI4, affording corresponding indole-3-carbamides 2 in moderate to high yields. In addition, the platinum-catalyzed cyclization of ortho-alkynylphenyl carbamates 3 afforded corresponding indole-3-carboxylates 4 in good yields. The present reaction proceeds through the intramolecular addition of carbon-nitrogen bonds to triple bonds, the so-called carboamination.
