114218-35-8 Usage
General Description
(-)-Metoprolol hydrochloride is a beta-adrenergic blocking agent often prescribed for the treatment of hypertension, angina pectoris, and heart failure. It works by blocking the action of certain natural chemicals in the body, such as epinephrine, on the heart and blood vessels. This helps to lower the heart rate, blood pressure, and strain on the heart. Metoprolol hydrochloride is a racemic mixture of two enantiomers, with the (-)-enantiomer being the more potent beta-adrenergic blocker. It is available in various forms, including tablets, extended-release tablets, and injection, and is commonly prescribed under the brand names Lopressor and Toprol XL. Common side effects of metoprolol hydrochloride include dizziness, tiredness, and a slow heartbeat.
Check Digit Verification of cas no
The CAS Registry Mumber 114218-35-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,2,1 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 114218-35:
(8*1)+(7*1)+(6*4)+(5*2)+(4*1)+(3*8)+(2*3)+(1*5)=88
88 % 10 = 8
So 114218-35-8 is a valid CAS Registry Number.
114218-35-8Relevant articles and documents
Kinetic resolution of aryl glycidyl ethers : A practical synthesis of optically pure β-blocker - S-metoprolol
Gurjar, Mukund K.,Sadalapure, Kashinath,Adhikari, Susanta,Sarma, Bugga V. N. B. S.,Talukdar, Arindam,Chorghade, Mukund S.
, p. 1471 - 1476 (2007/10/03)
Kinetic resolution of (±)-aryl glycidyl ethers using (R,R)-salen Co(III)OAc and water provided enantiomerically pure arylglycidyl ether and 1-arylglycerol derivatives with high enantiomeric excess. Application of this approach to (S)-metoprolol has been d
Highly efficient asymmetric hydrogenation of amino ketone derivatives leading to practical syntheses of (S)-propranolol and related compounds
Takahashi, Hisashi,Sakuraba, Shunji,Takeda, Hideo,Achiwa, Kazuo
, p. 5876 - 5878 (2007/10/02)
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