1142199-09-4

Basic information

• Product Name: (4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one
• Synonyms: (4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one
• CAS NO: 1142199-09-4
• Molecular Formula: C13H12ClNO4
• Molecular Weight: 281.69168
• Mol File: 1142199-09-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one(1142199-09-4)
• EPA Substance Registry System: (4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one(1142199-09-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1142199-09-4(Hazardous Substances Data)

Usage

General Description

(4E)-3-(chloromethyl)-4-(3,4-dimethoxybenzylidene)isoxazol-5(4H)-one is a chemical compound with a complex molecular structure. It contains a chloromethyl group, a benzylidene group, and an isoxazolone ring. The compound also features methoxy groups attached to the benzene ring. This chemical compound may have potential applications in the pharmaceutical industry, as isoxazolone derivatives have been studied for their potential biological activities, including antimicrobial, anticancer, and anti-inflammatory properties. However, further research and testing would be needed to fully understand the potential uses and effects of this specific compound.

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

Facile and expedient synthesis of α,β-unsaturated isoxazol-5(4H)-ones under mild conditions

Abstract: It was found that nano-SiO2–H2SO4 was catalyzed by the three-component cyclocondensation of aryl/heteroaryl aldehydes, hydroxylamine hydrochloride, and β-ketoesters toward the synthesis of α,β-unsaturated?isoxazol-5(4H)-ones under green conditions. The reaction yielded the corresponding heterocycles at room temperature in relatively shorter reaction times. It merits mentioning that the mild conditions allow the synthesis of several α,β-unsaturated?isoxazol-5(4H)-ones using this method. In this study, some new derivatives of isoxazolones were also synthesized and characterized. It is efficient, clean, simple, safe, and ecologically friendly. This straightforward method is cost-effective and requires no preparation of reactants. The three-component annulation was performed without using energy sources, for example, heat, ultrasound wave, and microwave irradiation. Graphic abstract: [Figure not available: see fulltext.].