1142363-56-1 Usage
Description
(2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester is a boronic acid ester that plays a crucial role in organic synthesis. It is characterized by the presence of a boron atom bonded to an oxygen and a carbon atom through double bonds, along with a pinacol group featuring two hydroxy groups attached to a carbon atom. This versatile chemical compound is widely utilized in the pharmaceutical and agrochemical industries for the synthesis of complex organic molecules.
Uses
Used in Organic Synthesis:
(2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester is used as a reagent in the Suzuki-Miyaura coupling reaction for the formation of carbon-carbon bonds. This reaction is a powerful tool in organic chemistry, enabling the creation of new compounds with potential applications in various fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester is employed as a key intermediate in the synthesis of complex organic molecules. These molecules can be further developed into potential drug candidates, contributing to the discovery and development of new therapeutic agents.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, (2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyran-4-yl)boronic acid, pinacol ester serves as a vital component in the synthesis of organic molecules with pesticidal or herbicidal properties. These molecules can be formulated into effective agrochemical products to protect crops and enhance agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1142363-56-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,2,3,6 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1142363-56:
(9*1)+(8*1)+(7*4)+(6*2)+(5*3)+(4*6)+(3*3)+(2*5)+(1*6)=121
121 % 10 = 1
So 1142363-56-1 is a valid CAS Registry Number.
1142363-56-1Relevant articles and documents
Synthesis of Pyranocyclopentaindolines Representing the Western Sections of Janthitrem B, JBIR-137, and Shearinine G
Fresia, Marvin,Lindel, Thomas
, (2022/02/05)
The synthesis of the ABCD tetracyclic partial structures of the fungal indole diterpenes janthitrem B, JBIR-137, and shearinine G is reported. The route starts from 5-formylated indoline that is coupled to a dihydropyran moiety, followed by Prins cyclization. A diene was obtained that was oxygenated in a divergent manner. The hydroxylated tetracyclic western half of janthitrem B was obtained in eight steps and 10 % overall yield. We also share our experience with alternative approaches passing via alkynylated precursors. This includes the gold-catalyzed cycloisomerization of a 6-ethynyl-5-prenylindoline.
INHIBITORS OF C-FMS KINASE
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Page/Page column 44, (2009/05/29)
The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, es
