114244-55-2

Upstream product

• 41670-98-8 3-O-benzyl-6-deoxy-1,2-O-isopropylidene-α-D-xylo-hept-6-enofuranos-5-ulose 
• 22529-61-9 (1R)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-5-yl)ethane-1,2-diol 
• 76801-66-6 5-deoxy-3-O-benzyl-1,2-O-isopropylidene-α-D-xylo-hexodialdo-1,4-furanose 
• 94844-71-0 1,2-O-Isopropyliden-6-O-methyl-5-desoxy-α-D-xylohexofuran-5-enose 
• 53167-11-6 1,2-O-isopropylidene-α-D-xylo-pentodialdo-1,4-furanose 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 35781-78-3 5,6-anhydro-3-O-benzyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 23313-03-3 (R)-2-[(3aR,5R,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]-2-hydroxyethyl 4-methylbenzenesulfonate 
• 18439-45-7 3-O-Benzyl-6-desoxy-1,2-O-isopropyliden-α-D-gluco-hexofuranose 
• 57032-39-0 3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-5-C-methyl-α-D-xylo-hex-5-enofuranose 

Downstream Products

• 114244-54-1 [(S)-2-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-propoxy]-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

General Homologation Strategy for Synthesis of l -glycero- and d -glycero-Heptopyranoses

A general and stereospecific homologation strategy for the synthesis of heptopyranosides is reported. The strategy employs the Wittig olefination and proline-catalyzed α-aminoxylation to achieve one carbon elongation and stereoselective hydroxylation at the C6 position, respectively. The l-glycero- and d-glycero-heptopyranosides can be obtained with nearly perfect stereoselectivity. Further study reveals the difference in the chemical shift of the C6 proton of l/d-glycero-heptopyranosyl diastereomers, which is found to be useful for assignment of the configuration of heptopyranosides.

1,3,5-TRIDEOXY-3,5-DI-C-METHYL-L-TALITOL: A CHIRON FOR THE C-33-C-37 SEGMENT OF AMPHOTERICIN B

1,3,5-Trideoxy-3,5-di-C-methyl-L-talitol is a potential chiron for the C-33-C-37 segment of amphotericin B.This hexitol has been synthesized from 3-O-benzyl-1,2-O-isopropylidene-α-D-glucofuranose by a route in which a C-methylene derivative at C-5 is hydr