114285-12-0Relevant academic research and scientific papers
A general and accurate nmr determination of the enantiomeric purity of α-aminoacids and α-aminoacid derivatives
Calmes, Monique,Daunis, Jacques,Jacquier, Robert,Verducci, Jean
, p. 2285 - 2292 (2007/10/02)
Derivatization of α-aminoacids, α-aminoesters and α-aminolactones as N-acetyl derivatives allow the accurate NMR determination of the enantiomeric purity. In these conditions the major coordination site with a chiral shift reagent will correspond to the NMR observation site. Experimental factors leading to the highest ΔΔδ values are ascertained. No straightforward correlation with absolute configurations can be established.
