114286-20-3Relevant articles and documents
Total Synthesis of (-)- and (+)-Botryodiplodin and (+)- and (-)-Epibotryodiplodin
Rehnberg, Nicola,Magnusson, Goeran
, p. 377 - 383 (2007/10/02)
the title compounds were prepared by the conjugate addition (d.e. more than 94percent) of LiMeCNCu to the chiral isoprene units (+)-(2R)- and (-)-(2S)-benzyloxy-2,5-dihydrofuran-4-carboxaldehyde (1r and 1s) followed by methyllithium-attack on the mixture
DIASTEREOSELECTIVE CONJUGATE ADDITION OF LITHIUM METHYLCYANOCUPRATE TO THE CHIRAL ISOPRENE UNITS 2-(R)- AND (S)-BENZYLOXY-2,5-DIHYDRO-4-FURANCARBOXALDEHYDE. TOTAL SYNTHESIS OF (-)- AND (+)-BOTRYODIPLODIN AND (+)- AND (-)-EPIBOTRYODIPLODIN.
Rehnberg, Nicola,Frejd, Torbjoern,Magnusson, Goeran
, p. 3589 - 3592 (2007/10/02)
Conjugate addition of lithium methylcyanocuprate to the title aldehydes proceeded with high diastereoselectivity (d.e. 94percent).Methyl lithium 1,2-addition, followed by Swern oxidation of the resulting alcohols, gave benzyl botryodiplodin and benzyl epi