1142948-08-0

Basic information

• Product Name: C₃₀H₃₁N₅O₃S₂
• Synonyms: C₃₀H₃₁N₅O₃S₂
• CAS NO: 1142948-08-0
• Molecular Weight: 573.74
• Mol File: 1142948-08-0.mol

Chemical Properties

• CAS DataBase Reference: C₃₀H₃₁N₅O₃S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₃₁N₅O₃S₂(1142948-08-0)
• EPA Substance Registry System: C₃₀H₃₁N₅O₃S₂(1142948-08-0)

Safety Data

• Hazardous Substances Data: 1142948-08-0(Hazardous Substances Data)

Upstream product

• 700804-06-4 4-(1-morpholin-4-yl-ethyl) phenylamine 
• 1142945-86-5 2-chloro-4-(4-methylthiophen-2-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 1143018-48-7 4-(4-methylthiophen-2-yl)-N-(4-(1-morpholinoethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.