1142953-82-9Relevant academic research and scientific papers
Regioselective synthesis of phenanthrenes and evaluation of their anti-oxidant based anti-inflammatory potential
Kanekar, Yogesh,Basha, Khalander,Duche, Sharad,Gupte, Rajan,Kapat, Arnab
supporting information, p. 454 - 463 (2013/10/01)
Regioselective synthesis of 9,10-Dihydro-2,5-Dimethoxyphenanthrene-1,7-diol (1) and 9,10-Dihydro-2,7-Dimethoxyphenanthrene-1,5-diol (2) was achieved using regioselective methylation, Wittig reaction, intramolecular cyclization and hydrogenation as key ste
TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST
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Page/Page column 12-13, (2009/09/07)
The present invention relates to novel synthetic toll like receptor antagonist. The present invention in particular provides compounds, methods and compositions for specifically inhibiting immune stimulation involving TLR ligands, especially TLR-4. The compounds are potentially useful in treatment of inflammation, autoimmunity, allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
