114326-27-1

Basic information

• Product Name: 6-methoxy-2-(naphthalen-2-ylmethyl)naphthalene-1-carboxylic acid
• CAS NO: 114326-27-1
• Molecular Formula: C₂₃H₁₈O₃
• Molecular Weight: 342.3872
• Mol File: 114326-27-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 569.6°C at 760 mmHg
• Flash Point: 203.7°C
• Density: 1.251g/cm³
• Vapor Pressure: 8.2E-14mmHg at 25°C
• Refractive Index: 1.692
• CAS DataBase Reference: 6-methoxy-2-(naphthalen-2-ylmethyl)naphthalene-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-2-(naphthalen-2-ylmethyl)naphthalene-1-carboxylic acid(114326-27-1)
• EPA Substance Registry System: 6-methoxy-2-(naphthalen-2-ylmethyl)naphthalene-1-carboxylic acid(114326-27-1)

Safety Data

• Hazardous Substances Data: 114326-27-1(Hazardous Substances Data)

Upstream product

• 66-99-9 β-naphthaldehyde 
• 114326-25-9 6-methoxy-1-naphthoic acid diethylamide 
• 114326-26-0 7-Methoxy-3-naphthalen-2-yl-3H-naphtho[1,2-c]furan-1-one 

Downstream Products

• 114326-29-3 7,14-dimethyl-3-methoxydibenzanthracene 
• 114326-35-1 7,14-dimethyldibenzanthracene-3,4-dione 
• 114326-33-9 (+/-)-trans-3,4-dihydroxy-3,4-dihydrodibenz[a,j]anthracene 
• 114326-30-6 3-hydroxy-7,14-dimethyldibenzanthracene 
• 114326-31-7 dibenzanthracene-3,4-dione 
• 83136-28-1 3-methoxydibenzanthracene 
• 83136-32-7 3-hydroxydibenzanthracene 
• 114326-34-0 (+/-)-trans-3,4-dihydroxy-syn-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene 
• 114326-28-2 3-methoxy-14-acetoxydibenzanthracene 

Relevant articles and documents

Synthesis of the Tumorigenic 3,4-Dihydrodiol Metabolites of Dibenzanthracene and 7,14-Dimethyldibenzanthracene

Synthses are described of the trans-3,4-dihydrodiol derivatives (2a and 2b) of dibenzanthracene and 7,14-dimethyldibenzanthracene (1a and 1b), implicated as their proximate carcinogenic metabolites.Conversion of 2a to the bay region anti-diol epoxide derivative 3a, its putative ultimate carcinogenic metabolite, is also reported.The related diol epoxide derivative of 2b could not be prepared due to its chemical instability.Tumorigenicity assays confirm that 1b and 2b are potent carcinogens on mouse skin, while 1a and 2a are only relatively weakly active.The diol epoxide 3a exhibited significantly higher tumorigenicity than its dihydrodiol precursor 2a.These findings are consistent with the hypothesis that the bay region diol epoxide metabolites are the active carcinogenic forms of these hydrocarbons.They also support the generalization that methyl substitution in bay regions enhances the carcinogenic activity of polycyclic aromatic hydrocarbons.