114335-54-5 Usage
General Description
2-Amino-3-hydroxy-4-bromopyridine, also known as 4-Bromo-2-amino-3-pyridinol, is a chemical compound with the molecular formula C5H6BrNO. It is a brominated derivative of pyridine, containing an amine and hydroxy group. 2-Amino-3-hydroxy-4-bromopyridine is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as a building block in organic synthesis. It has been found to have anti-inflammatory properties and is being studied for potential medical applications. 2-Amino-3-hydroxy-4-bromopyridine is also used in the production of dyes and pigments, and as a reagent in various chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 114335-54-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,3,3 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 114335-54:
(8*1)+(7*1)+(6*4)+(5*3)+(4*3)+(3*5)+(2*5)+(1*4)=95
95 % 10 = 5
So 114335-54-5 is a valid CAS Registry Number.
InChI:InChI=1S/C5H5BrN2O/c6-3-1-2-8-5(7)4(3)9/h1-2,9H,(H2,7,8)
114335-54-5Relevant articles and documents
SUBSTITUTED HETEROCYCLIC COMPOUNDS AS CRAC MODULATORS
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Paragraph 0349, (2016/06/13)
The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators. wherein, ring D is Formula (a) or Formula (b): A and B, which may be same or different, are independently CR3 or N; Y is CR3 or N; L is selected from —NR2C(O)—, —C(O)NR2— and —NR2CRaRb—; Ra and Rb are independently hydrogen, halogen or substituted or unsubstituted alkyl; ring E is selected from the Formula (i) to (vii).
