1143516-79-3Relevant academic research and scientific papers
Stereoselective synthesis of the C1-C12 segment of iriomoteolide-1a: a very potent macrolide antitumor agent
Ghosh, Arun K.,Yuan, Hao
, p. 1416 - 1418 (2009)
A stereoselective synthesis of the C1-C12 segment of the potent cytotoxic macrolide, iriomoteolide 1a, has been accomplished. The key steps involve an enzymatic kinetic resolution of a β-hydroxy amide, a Pd-catalyzed cross-coupling t
