1143525-35-2 Usage
Uses
Used in Pharmaceutical Synthesis:
1-Cbz-3-Methylazetidine-3-carboxylic acid is used as a building block for the synthesis of pharmaceuticals, leveraging its structural properties to create a variety of medicinal compounds. Its presence in the synthesis process aids in the development of drugs with specific therapeutic targets.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
In the field of asymmetric synthesis, 1-Cbz-3-Methylazetidine-3-carboxylic acid is utilized as a chiral auxiliary. This application is significant for the production of enantiomerically pure compounds, which are essential in pharmaceuticals where the stereochemistry of a molecule can greatly affect its biological activity and efficacy.
Used in Catalytic Reactions as a Ligand:
1-Cbz-3-Methylazetidine-3-carboxylic acid also serves as a ligand in catalytic reactions. Its use in this capacity can enhance the selectivity and efficiency of various organic reactions, contributing to the advancement of synthetic methodologies in organic chemistry.
Used in Organic Chemistry Research:
In the realm of academic and industrial research, 1-Cbz-3-Methylazetidine-3-carboxylic acid is employed for exploring new reactions and mechanisms, further expanding the understanding of organic chemistry and potentially leading to new applications and discoveries.
Check Digit Verification of cas no
The CAS Registry Mumber 1143525-35-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,3,5,2 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1143525-35:
(9*1)+(8*1)+(7*4)+(6*3)+(5*5)+(4*2)+(3*5)+(2*3)+(1*5)=122
122 % 10 = 2
So 1143525-35-2 is a valid CAS Registry Number.
1143525-35-2Relevant academic research and scientific papers
HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS
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, (2020/06/05)
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein R1, R2, R4, R5, R6, R7, R8, R9, R10,Z, X1, X2, X3, L2, HET, n and q are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.
1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors
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Page/Page column 19, (2008/06/13)
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of For
