1143534-72-8

Basic information

• Product Name: tert-butyl (S)-(1-(4-chlorophenyl)-3-hydroxypropyl)carbamate
• Synonyms: tert-butyl (S)-(1-(4-chlorophenyl)-3-hydroxypropyl)carbamate
• CAS NO: 1143534-72-8
• Molecular Weight: 285.771
• Mol File: 1143534-72-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl (S)-(1-(4-chlorophenyl)-3-hydroxypropyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (S)-(1-(4-chlorophenyl)-3-hydroxypropyl)carbamate(1143534-72-8)
• EPA Substance Registry System: tert-butyl (S)-(1-(4-chlorophenyl)-3-hydroxypropyl)carbamate(1143534-72-8)

Safety Data

• Hazardous Substances Data: 1143534-72-8(Hazardous Substances Data)

Upstream product

• 131690-60-3 (S)-β-amino-β-(4-chlorophenyl)propionic acid 
• 1149755-70-3 C₁₄H₁₈ClNO₃ 
• 1213362-28-7 (3S)-3-amino-3-(4-chlorophenyl)propan-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1143534-74-0 (S)-3-(tert-butoxycarbonylamino)-3-(4-chlorophenyl)propyl methanesulfonate 
• 1296852-29-3 (S)-1-(4-chlorophenyl)-3-(piperidin-1-yl)propan-1-amine 
• 1296863-10-9 (S)-1-(4-chlorophenyl)-3-(pyrrolidin-1-yl)propan-1-amine 
• 1143533-32-7 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-pyrrolidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide 
• 1143533-26-9 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-piperidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide 

Relevant articles and documents

Deep learning-driven scaffold hopping in the discovery of Akt kinase inhibitors

Scaffold hopping has been widely used in drug discovery and is a topic of high interest. Here a deep conditional transformer neural network, SyntaLinker, was applied for the scaffold hopping of a phase III clinical Akt inhibitor, AZD5363. A number of nove

A designer axially chiral amino sulfonamide as an efficient organocatalyst for direct asymmetric mannich reactions of N-boc-protected imines

The moderate nucleophilicity of the axially chiral amino sulfonamide (S)-1 suppresses the problematic side reactions, including aldol reactions, in the asymmetric Mannich reaction of N-Boc-protected imines with aldehydes. The corresponding adducts are obtained in good yield and excellent stereoselectivity (see scheme; Boc=tert-butoxycarbonyl, Tf=trifluoromethanesulfonyl).