1143577-98-3

Upstream product

• 756751-88-9 1-(5-chloropyridin-3-yl)-4-tert-butoxycarbonylpiperazine 
• 98-80-6 phenylboronic acid 
• 412348-60-8 4-(5-bromo-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1206597-53-6 4-(6-iodo-5-phenyl-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PIPERAZIN-1-YL-TRIFLUOROMETHYL-SUBSTITUTED-PYRIDINES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS

The present invention relates to piperazin-1-yl-trifluoromethyl-substituted-pyridines that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects. Formula (I).

AMIDE COMPOUND

An object of the present invention is to provide a novel fused-ring compound which has a FAAH inhibitory effect and is useful as an analgesic. The present invention relates to a compound represented by formula (I): wherein symbols are as defined in the specification, or salt thereof.