114365-12-7

Basic information

• Product Name: N-(4-(2-aMinoethyl)phenyl)MethanesulfonaMide
• Synonyms: N-(4-(2-aMinoethyl)phenyl)MethanesulfonaMide
• CAS NO: 114365-12-7
• Molecular Formula: C₉H₁₄N₂O₂S
• Molecular Weight: 214.28466
• Mol File: 114365-12-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-(2-aMinoethyl)phenyl)MethanesulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(2-aMinoethyl)phenyl)MethanesulfonaMide(114365-12-7)
• EPA Substance Registry System: N-(4-(2-aMinoethyl)phenyl)MethanesulfonaMide(114365-12-7)

Safety Data

• Hazardous Substances Data: 114365-12-7(Hazardous Substances Data)

Upstream product

• 144226-16-4 (tert-butoxy)-N-[2-(4-nitrophenyl)-ethyl]-carboxamide 
• 1204820-34-7 tert-butyl N-[2-[4-(methanesulfonamido)phenyl]ethyl]carbamate 
• 94838-59-2 tert-butyl 4-aminophenethylcarbamate 
• 33893-37-7 N-(4-cyanomethylphenyl)methanesulfonamide 
• 3544-25-0 p-aminophenylacetonitrile 

Downstream Products

• 944742-46-5 2-cyclopropyl-3H-imidazo[4,5-b]pyridine-7-carboxylic acid [2-(4-methanesulfonylamino-phenyl)-ethyl]-amide 

Relevant articles and documents

Compound with degrading STAT3 enzyme and preparation method and pharmaceutical application thereof

The present invention relates to a compound represented by general formula (I) or a stereoisomer thereof. Use of deuterated, solvates, prodrugs, metabolites, pharmaceutically acceptable salts or co-crystals, and intermediates and preparation methods, and in STAT3-related diseases such as tumors. B-L-K(I).

Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists

The structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. The 2-halogen analogues showed enhanced antagonism compared to the prototype antagonist.