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114377-40-1

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114377-40-1 Usage

General Description

1-(benzyloxy)-2-Methylpropan-2-aMine is a chemical compound that belongs to the class of amines. It is an organic compound with a molecular formula of C11H17NO. 1-(benzyloxy)-2-Methylpropan-2-aMine is a derivative of amphetamines and is commonly used as a precursor in the synthesis of various pharmaceutical drugs, such as amphetamines and other psychoactive substances. It is also used in the field of medicinal chemistry for the development of new drugs. The compound is typically used in the form of its hydrochloride salt, and it has stimulant and psychoactive properties, making it important in the field of pharmacology and drug discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 114377-40-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,3,7 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114377-40:
(8*1)+(7*1)+(6*4)+(5*3)+(4*7)+(3*7)+(2*4)+(1*0)=111
111 % 10 = 1
So 114377-40-1 is a valid CAS Registry Number.

114377-40-1Relevant articles and documents

NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS

-

, (2019/05/15)

The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Synthesis, in vitro metabolic studies, and antitumour activity of methyl analogues of ifosfamide

Misiura, Konrad,Kardacka, Karina,Kusnierczyk, Halina

, p. 291 - 294 (2007/10/03)

Synthesis of 2-chloro-1,1-dimethylethyl and 2-chloro-2,2-dimethylethyl analogues of ifosfamide was performed via aziridine intermediate. In vitro metabolic activation showed that both compounds are metabolised at a rate similar to the parent drug. However, their anticancer activity against L1210 leukaemia in mice was lower as compared with ifosfamide. The reduction of antitumour efficiency of examined analogues is probably caused by a lower ability to cross-link DNA by their final, active metabolites.

Azaoxindole derivatives

-

, (2008/06/13)

This invention relates to novel 4-, 5-, 6-, and 7-azaoxindole derivatives. The compounds are anti-inflammatory and analgesic agents and inhibitors of one or more of prostaglandin H2 synthase, 5-lipoxygenase and interleukin-1 biosynthesis. They are useful in the treatment of chronic inflammatory diseases, allergy, psoriasis, various bone diseases, and immune dysfunctions such as systemic lupus erythematosis.

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