114382-19-3Relevant academic research and scientific papers
Discovery of Potent and Selective RSK Inhibitors as Biological Probes
Jain, Rama,Mathur, Michelle,Lan, Jiong,Costales, Abran,Atallah, Gordana,Ramurthy, Savithri,Subramanian, Sharadha,Setti, Lina,Feucht, Paul,Warne, Bob,Doyle, Laura,Basham, Stephen,Jefferson, Anne B.,Lindvall, Mika,Appleton, Brent A.,Shafer, Cynthia M.
, p. 6766 - 6783 (2015/09/22)
While the p90 ribosomal S6 kinase (RSK) family has been implicated in multiple tumor cell functions, the full understanding of this kinase family has been restricted by the lack of highly selective inhibitors. A bis-phenol pyrazole was identified from hig
