1143863-58-4

Basic information

• Product Name: 3-(2-fluorophenyl)-4H-chroMen-4-one
• Synonyms: 3-(2-fluorophenyl)-4H-chroMen-4-one
• CAS NO: 1143863-58-4
• Molecular Formula: C₁₅H₉FO₂
• Molecular Weight: 240.2291632
• Mol File: 1143863-58-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-fluorophenyl)-4H-chroMen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-fluorophenyl)-4H-chroMen-4-one(1143863-58-4)
• EPA Substance Registry System: 3-(2-fluorophenyl)-4H-chroMen-4-one(1143863-58-4)

Safety Data

• Hazardous Substances Data: 1143863-58-4(Hazardous Substances Data)

Upstream product

• 1993-03-9 o-fluorophenylboronic acid 
• 122775-34-2 3-iodo-chromen-4-one 
• 49619-82-1 3-bromo-4H-chromen-4-one 

Downstream Products

• 950486-73-4 C₁₆H₁₂FN₃O 
• 950486-71-2 C₁₇H₁₃FN₂O 
• 1143863-66-4 3-(2-fluorophenyl)chroman-4-one 

Relevant articles and documents

Synthesis and biological evaluation of novel 2,4,5-substituted pyrimidine derivatives for anticancer activity

A series of novel 2,4,5-substituted pyrimidine derivatives were synthesized and evaluated for inhibition against the human hepatocellular carcinoma BEL-7402 cancer cell line. Several compounds showed potent inhibition with an IC50 value less than 0.10 μM. Structure-activity relationships for this class of compounds at the 2- and 5-position of the pyrimidine scaffold have been elucidated. The most active compound 7gc showed good inhibition of several different human cancer cell lines with IC50 values from 0.024 to 0.55 μM.