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1-(2-nitrobenzyl)-1H-pyridin-2-one is a chemical compound with the molecular formula C12H9N2O3. It is a derivative of 1H-pyridin-2-one, featuring a nitrobenzyl group attached to the 1-position. 1-(2-nitrobenzyl)-1H-pyridin-2-one is characterized by its yellow crystalline appearance and is soluble in organic solvents such as ethanol and acetone. It is synthesized through a condensation reaction between 2-amino-1-(2-nitrophenyl)ethanone and ethyl acetoacetate, followed by hydrolysis and decarboxylation. 1-(2-nitrobenzyl)-1H-pyridin-2-one has potential applications in the pharmaceutical industry, particularly as a precursor for the synthesis of various biologically active compounds, such as inhibitors and antagonists. Its chemical structure and properties make it a valuable intermediate in the development of new drugs and therapeutic agents.

1144-79-2

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1144-79-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1144-79-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1144-79:
(6*1)+(5*1)+(4*4)+(3*4)+(2*7)+(1*9)=62
62 % 10 = 2
So 1144-79-2 is a valid CAS Registry Number.

1144-79-2Downstream Products

1144-79-2Relevant academic research and scientific papers

Environmentally benign nucleophilic substitution reaction of arylalkyl halides in water using CTAB as the inverse phase transfer catalyst

Godha, Atul K.,Thiruvengadam, Jayaraman,Abhilash, Viswanadhan,Balgi, Prajwal,Narayanareddy,Vignesh, Kumaresan,Gadakh, Amol V.,Sathiyanarayanan,Ganesh, Sambasivam

, p. 16041 - 16045 (2019)

An environmentally benign, practically scalable and highly selective C-arylalkylation of active methylene compounds is developed using CTAB as the inverse phase transfer catalyst in water. The methodology developed is elaborated into the one-pot synthesis of quinoline derivatives and also applicable to the regioselective N-aralkyl of 2-pyridones.

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