1144030-27-2Relevant academic research and scientific papers
Stereodivergent access to polyhydroxylated 10-azabicyclo[4.3.1]decanes as new calystegine analogues
Chagnault, Vincent,Compain, Philippe,Lewinski, Krzysztof,Ikeda, Kyoko,Asano, Naoki,Martin, Olivier R.
supporting information; experimental part, p. 3179 - 3182 (2009/09/05)
A rapid and stereodivergent access to polyhydroxylated 10- azabicyclo[4.3.1]decanes as new calystegine analogues by way of a double benzotriazolyl/carbon nucleophile exchange followed by a ring-closing metathesis was achieved. Preliminary evaluation of the new compounds as glucocerebrosidase inhibitors was also performed.
