1144045-36-2Relevant academic research and scientific papers
Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists
Shao, Yuefei,Cole, Andrew G.,Brescia, Marc-Raleigh,Qin, Lan-Ying,Duo, Jingqi,Stauffer, Tara M.,Rokosz, Laura L.,McGuinness, Brian F.,Henderson, Ian
scheme or table, p. 1399 - 1402 (2009/10/15)
A series of trisubstituted purinones was synthesized and evaluated as A2A receptor antagonists. The A2A structure-activity relationships at the three substituted positions were studied and selectivity against the A1 recept
