Cas 1144070-82-5,1-{4-[1-ethyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-(6-morpholin-4-ylpyridin-3-yl)urea

1144070-82-5

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Basic information

Product Name: 1-{4-[1-ethyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-(6-morpholin-4-ylpyridin-3-yl)urea
Synonyms:
CAS NO:1144070-82-5
Molecular Formula:
Molecular Weight: 555.64
EINECS: N/A
Product Categories: N/A
Mol File: 1144070-82-5.mol
Article Data: 2

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-{4-[1-ethyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-(6-morpholin-4-ylpyridin-3-yl)urea(CAS DataBase Reference)
NIST Chemistry Reference: 1-{4-[1-ethyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-(6-morpholin-4-ylpyridin-3-yl)urea(1144070-82-5)
EPA Substance Registry System: 1-{4-[1-ethyl-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}-3-(6-morpholin-4-ylpyridin-3-yl)urea(1144070-82-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1144070-82-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1144070-82-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,4,0,7 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1144070-82:
(9*1)+(8*1)+(7*4)+(6*4)+(5*0)+(4*7)+(3*0)+(2*8)+(1*2)=115
115 % 10 = 5
So 1144070-82-5 is a valid CAS Registry Number.

1144070-82-5Upstream product

52023-68-4 6-(morpholin-4-yl)pyridin-3-amine

1144070-82-5Downstream Products

1144070-82-5Relevant articles and documents

Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: Discovery of highly potent and selective analogs with improved human microsomal stability

Richard, David J.,Verheijen, Jeroen C.,Curran, Kevin,Kaplan, Joshua,Toral-Barza, Lourdes,Hollander, Irwin,Lucas, Judy,Yu, Ker,Zask, Arie

scheme or table, p. 6830 - 6835 (2010/07/05)

A series of highly potent and selective pyrazolopyrimidine mTOR inhibitors which contain water-solubilizing groups attached to the 6-arylureidophenyl moiety have been prepared. Such derivatives displayed superior potency to those in which these appendages

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