114419-88-4

Basic information

• Product Name: (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE
• Synonyms: (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE
• CAS NO: 114419-88-4
• Molecular Formula: C₁₁H₁₅N
• Molecular Weight: 161.24
• Mol File: 114419-88-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE(114419-88-4)
• EPA Substance Registry System: (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE(114419-88-4)

Safety Data

• Hazardous Substances Data: 114419-88-4(Hazardous Substances Data)

Usage

General Description

"(R)-N-Methyl-1,2,3,4-tetrahydronaphthalen-1-amine" is a chemical compound commonly known as "1- tetralinamine". It is an organic amine that is used as a reagent in chemical synthesis. (R)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE is a stereoisomer of the racemic 1-tetralinamine and is used in the production of pharmaceuticals and other organic compounds. It is a colorless liquid with a strong odor and is soluble in organic solvents such as ethanol and diethyl ether. "(R)-N-Methyl-1,2,3,4-tetrahydronaphthalen-1-amine" is an important building block in organic chemistry and is used in the synthesis of various molecules.

Upstream product

• 10409-15-1 (-)-N-methyl-1,2,3,4-tetrahydro-1-naphthylamine 
• 23357-46-2 (R)-1,2,3,4-Tetrahydro-1-naphthylamine 
• 1562430-72-1 (R)-N-benzyl-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine 
• 922516-02-7 (R)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)formamide 
• 114419-89-5 (R)-N-methyl-1,2,3,4-tetrahydro-1-naphthylamine (+)-dibenzoyltartrate 

Downstream Products

• 1263775-58-1 N-methyl-3-{1-[2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetyl]-piperidin-4-yl}-N-(R)-1,2,3,4-tetrahydro-naphthalene-1-yl-benzamide 

Relevant articles and documents

Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst

A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst containing a P-stereogenic MaxPHOX ligand is described for the direct asymmetric hydrogenation of N-methyl and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile tetrahydrofuran ligand allows for effective activation and reactivity, even at low temperatures. Density functional theory calculations allowed the rationalization of the stereochemical course of the reaction.

IAP ANTAGONISTS

There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (lAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing said compounds.

FUNGICIDAL CARBOXAMIDES

This invention is directed to compounds of Formula (1) including all geometric and stereoisomers, N oxides, and agriculturally suitable salts thereof, agricultural compositions containing them and their use as fungicides, ( l ) provided that the compound of Formula 1 is other than 2-[1-[(2-chlorophenyl)acetyl]-4-piperidinyl]-N-methyl-N-[(1R)-1-phenylethyl]-4-thiazolecarboxamide and R1 is other than 4-fluorophenyl; wherein R1, R2, A, G, Q, W1, W2, X and n are otherwise as defined in the disclosure, Also disclosed are compositions containing the a compound having a formula corresponding to Formula 1 where the provisos are both omitted; and methods for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound having a formula corresponding to Formula (1) where the provisos are both omitted.