114426-08-3Relevant articles and documents
Hydrazide-containing inhibitors of HIV-1 integrase
Zhao, He,Neamati, Nouri,Sunder, Sanjay,Hong, Huixiao,Wang, Shaomeng,Milne, George W. A.,Pommier, Yves,Burke Jr., Terrence R.
, p. 937 - 941 (2007/10/03)
Inhibitors of HIV integrase are currently being sought as potential new therapeutics for the treatment of AIDS. A large number of inhibitors discovered to date contain the o-bis-hydroxy catechol structure. In an effort to discover structural leads for the
3,5-diphenyl-1H-pyrazole derivatives. VII - esters, 2-dialkylaminoethyl ethers and N-substituted carbamates of 1-(2- hydroxy-3-phenoxypropyl)-3,5-diphenyl-1H-pyrazole with depressant and platelet antiaggregating activities
Bruno,Bondavalli,Ranise,Schenone,Losasso,Cenicola,Stella,Donnoli,Marmo
, p. 527 - 543 (2007/10/02)
The syntheses of 1-(2-hydroxy-3-phenoxypropyl)-3,5-diphenyl- 1H-pyrazole 2 by reaction of 1-hyrazino-3-phenoxy-2-propanol with dibenzoylmethane, of esters 3 and 2-dialkylaminoethyl ethers 4 starting from 2 as sodium salt and acyl chlorides or 2-chloroethy