1144502-33-9Relevant academic research and scientific papers
CARBON LINKED MODULATORS OF gamma-SECRETASE
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Page/Page column 17, (2009/05/29)
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, R1, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
PIPERIDINYL AND PIPERAZINYL MODULATORS OF y-SECRETASE
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Page/Page column 29, (2009/05/29)
The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
AMINE LINKED MODULATORS OF y-SECRETASE
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Page/Page column 23, (2009/05/29)
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, X, Y, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
BIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES THEREOF
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Page/Page column 9, (2009/05/29)
The present invention relates to compounds having the general Formula (I) with the definitions of R1, R2, R3, and R4 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of s
GSM INTERMEDIATES
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Page/Page column 83, (2009/05/28)
The present invention relates the use of compounds having the general Formula I, wherein the definitions or R1 and R2 are provided in the specification. Said compounds of Formula I are useful for the synthesis of a variety of g-secretase modulators, which are in turn useful for the treatment of diseases associated with y-secretase activity, including Alzheimer′s disease.
AMIDE LINKED MODULATORS OF Gamma-SECRETASE
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Page/Page column 14, (2009/05/29)
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, R1 R2, R3, R4, R5, R6, R7, and R8 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with gamm
