1144503-24-1

Basic information

• Product Name: dimethyl N-benzyl-3,4-bis(3,4,5-trimethoxyphenyl)pyrrole-2,5-dicarboxylate
• Synonyms: dimethyl N-benzyl-3,4-bis(3,4,5-trimethoxyphenyl)pyrrole-2,5-dicarboxylate
• CAS NO: 1144503-24-1
• Molecular Weight: 605.642
• Mol File: 1144503-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl N-benzyl-3,4-bis(3,4,5-trimethoxyphenyl)pyrrole-2,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl N-benzyl-3,4-bis(3,4,5-trimethoxyphenyl)pyrrole-2,5-dicarboxylate(1144503-24-1)
• EPA Substance Registry System: dimethyl N-benzyl-3,4-bis(3,4,5-trimethoxyphenyl)pyrrole-2,5-dicarboxylate(1144503-24-1)

Safety Data

• Hazardous Substances Data: 1144503-24-1(Hazardous Substances Data)

Upstream product

• 1144503-16-1 dimethyl N-benzyl-3,4-bis(trifluoromethanesulfonyloxy)pyrrole-2,5-dicarboxylate 
• 182163-96-8 3,4,5-trimethoxyphenylboronic Acid 

Downstream Products

• 220231-01-6 3,4-bis-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid dimethyl ester 

Relevant articles and documents

A general method for the synthesis of N-unsubstituted 3,4-diarylpyrrole-2, 5-dicarboxylates

A general method for the synthesis of N-unsubstituted 3,4-diarylpyrrole-2, 5-dicarboxylates (3) has been developed. The key reactions involved are the Hinsberg-type synthesis of dimethyl N-benzyl-3,4-dihydroxypyrrole-2,5- dicarboxylate (6) followed by palladium-catalyzed Suzuki-Miyaura coupling of its bis-triflate derivative (7). The N-benzyl protecting group of the resulting 3,4-diaryl pyrrole-2,5-dicarboxyl ates (8) is cleanly removed under hydrogenolytic or solvolytic conditions.