1144520-01-3

Basic information

• Product Name: C₁₇H₂₀Cl₂N₂O₃
• CAS NO: 1144520-01-3
• Molecular Weight: 371.263
• Mol File: 1144520-01-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₀Cl₂N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₀Cl₂N₂O₃(1144520-01-3)
• EPA Substance Registry System: C₁₇H₂₀Cl₂N₂O₃(1144520-01-3)

Safety Data

• Hazardous Substances Data: 1144520-01-3(Hazardous Substances Data)

Upstream product

• 1144519-79-8 C₁₁H₁₇BrN₂O₃ 
• 151169-74-3 2,3-dichlorobenzeneboronic acid 

Downstream Products

• 1174342-90-5 C₁₆H₁₉Cl₂N₅O₂ 

Relevant articles and documents

(2-Aryl-5-methylimidazol-4-ylcarbonyl)guanidines and (2-aryl-5-methyloxazol-4-ylcarbonyl)guanidines as NHE-1 inhibitors

A series of (2-aryl-5-methylimidazol-4-ylcarbonyl)guanidines and (2-aryl-5-methyloxazol-4-ylcarbonyl)guanidines were synthesized and evaluated as NHE-1 inhibitors. The structure-activity relationships well matched those of furan derivatives, which were previously investigated. The (2,5-disubstituted)phenyl compounds showed better activities than the other analogues in both imidazole and oxazole compounds. Especially, 2-(2,5-dichlorophenyl)imidazole 52, and 2-(2-methoxy-5-chlorophenyl)imidazole 54 compounds exhibited potent cardioprotective efficacy both in vitro and in vivo as well as high NHE-1 inhibitory activities.