114473-85-7Relevant academic research and scientific papers
A NOVEL SYNTHETIC METHOD OF LACTAMS FROM 1,3-DIOXIN-4-ONES VIA INTRAMOLECULAR KETENE TRAPPING
Sato, Masayuki,Ogasawara, Hiromichi,Takayama, Kazuhisa,Kaneko, Chikara
, p. 2611 - 2614 (2007/10/02)
A novel route to four- and five-membered lactams from 1,3-dioxin-4-ones having an α-aminoalkyl side-chain at 5- or 6-position through cycloreversion to acylketenes followed by intramolecular ketene trapping by the amino function is described.
