114475-33-1

Upstream product

• 114475-31-9 tert-Butyl (3S,4RS)-3-<(tert-Butoxycarbonyl)amino>-4-hydroxy-5-hexenoate 
• 131792-07-9 tert-Butyl (3S,4RS)-4-Acetoxy-3-<(tert-butoxycarbonyl)amino>-5-hexenoate 
• 153248-79-4 N-α-(tert-butoxycarbonyl)-β-tert-butyl-L-aspartal 
• 114475-41-1 3-Phenyl-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid benzyl ester 

Downstream Products

• 114475-37-5 1-Benzyl 7-tert-Butyl (4RS,5S)-4-Bromo-5-<(tert-butoxycarbonyl)amino>-2-phenylheptenedioate 
• 114475-39-7 Boc-Asp(O-tBu)ψ-D,L-Phe-OBn 
• 114475-35-3 1-Benzyl 7-tert-Butyl (4RS,5S)-5-<(tert-Butoxycarbonyl)amino>-4-hydroxy-2-phenyl-2-heptenedioate 
• 114475-35-3 (E)-(S)-2-Benzyl-5-tert-butoxycarbonylamino-4-hydroxy-hept-2-enedioic acid 1-benzyl ester 7-tert-butyl ester 
• 114475-42-2 (E)-2-Benzyl-3-((2R,3S)-3-tert-butoxycarbonylamino-5-oxo-tetrahydro-furan-2-yl)-acrylic acid benzyl ester 
• 114475-43-3 (E)-2-Benzyl-3-((2S,3S)-3-tert-butoxycarbonylamino-5-oxo-tetrahydro-furan-2-yl)-acrylic acid benzyl ester 

Relevant academic research and scientific papers

Novel Methodology for the Synthesis of trans-Alkene Dipeptide Isosteres

Natural amino acids were converted to the corresponding allylic alcohols A, from which key precursors C were obtained via a three-step sequence .The allylic alcohols D were furt

AMIDE BOND SURROGATES: A GENERAL SYNTHETIC ROUTE TO TRANS CARBON-CARBON DOUBLE BOND ISOSTERES.

A practical synthesis toward trans double bond replacements of amide bond pseudopeptides has been accomplished.This methodology provides a general route to a wide range of modified peptide analogs which may have biological significance.